http://www.medicalnewstoday.com/articles/246619.php
Keypoints:
a. they found virus replicating factory inside the tumor
b. they didn't find the virus replicating factory in normal tissue.
c. the virus evaded immune system
Because virus can be engineered to add a little gene to create a potent cancer toxin, so reovirus become a perfect delivery system.
But c. is also scary. and b. is important for the safety of patient.
---------------- Whacky idea alert -------------------------------------
What if we re-engineer a mastitis virus, something that home into breast cancer cells to replicate inside a breast cancer cell?
Other gene therapy platform:
http://www.mdanderson.org/newsroom/news-releases/2011/gene-therapy-kills-breast-cancer-stem-cells-boosts-chemotherapy.html
http://www.mdanderson.org/newsroom/news-releases/2011/gene-therapy-kills-breast-cancer-stem-cells-boosts-chemotherapy.html
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