Wednesday, July 4, 2012

MMTV virus in breast cancer



 Unfortunately, even if there is a cure based on this interesting findings, it will take 15 years to go through clinical trials and 1 billion dollars.   In the meanwhile, it needs to compete with 100s of promising drugs (which turn out to be duds) for patients, researchers and dollars.   It's possible it may lose in the early competition for lack of tweaking, lack of patients, lack of money and languish forever.
That's why I keep trumpeting the virtues of ispy-2 trial, and other new clinical trial designs.    Cancer evolve drug resistance fast,  cancer drugs development is too slow in the last 30 years.  
Cancer drug development is sadly lagging the AIDS drug development.  AIDS bursted unto the scene in 1980s, killing its patients within 1 year.   The urgency of AIDS epidemic translated to 10% of NIH funding and massive researching effort and within 10 years, science worked out many of the previous unknowns and there were multiple drugs that target HIV.   Now AIDS patients could look forward to a normal life expectancy.   AIDS was the greatest challenge and the greatest triumph of modern medicine.
Metastatic breast cancer or lung cancer is not there yet.

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