What a holy grail cure might look like?

7/8 complete response. This drug will definitely be fast tracked for this indication.  Yes it's a great development! No it's not for breast cancer, though a small percentage of breast cancer may ultimately benefit (inflammatory breast cancer folks should look for clinical trials).
 http://www.fiercepharma.com/story/pfizers-targeted-drug-knocks-out-child-cancers-small-study/2012-05-17 

 I'm not saying we should snub our noses at the drugs that is yielding 5%, 25% or 50% complete responses. the 5% complete response may well be harbinger of a targeted therapy that can be 90% complete response for a small subset of the very diverse breast cancers. Every small step is cause for celebration and many paths to the cure need to be explored. But this is what "cure" should look like. Targeted and effective. Till we have this kind of treatment for 99% of metastatic breast cancers, no one is a survivor.