Thursday, October 3, 2013

Triple-negative tumors targetted with cystine transporter blocker

http://www.eurekalert.org/pub_releases/2013-10/uoc--tbc100213.php

Timmerman found that she could significantly slow growth of triple-negative tumors using an FDA-approved anti-inflammatory drug called sulfasalazine to block a specific cystine transporter called xCT. While sulfasalazine itself would not be appropriate for treating cancer, Timmerman said, it could serve as a "lead compound" that could be used to develop drugs that specifically target xCT on tumor cells.

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